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dc.contributor.authorDočkalová, Hana
dc.contributor.authorHorký, Pavel
dc.contributor.authorZeman, Ladislav
dc.contributor.authorSkládanka, Jiří
dc.date.accessioned2021-06-15T00:02:14Z
dc.date.available2021-06-15T00:02:14Z
dc.date.issued2018
dc.identifier43914708
dc.identifier.issn1338-0230 Sherpa/RoMEO, JCR
dc.identifier.urihttps://repozitar.mendelu.cz/xmlui/handle/20.500.12698/1285
dc.description.abstractMilk thistle (Silybum marianum) is one of the best known and very often used herbs with positive effect on liver. The aim of this article was to study influence of addition of milk thistle pressed parts in feed ration on liver histology and weight increase of laboratory rats. The experiment was tested by 15 pieces of laboratory rats divided into 3 groups (A, B, C). The rats in first group (A) hade feed ration with addition of 10% milk thistle pressed parts, second group (B) hade feed ration with 20% and control group (C) hade feed ration without addition of milk thistle pressed parts. The silymarin content of pressed milk thistle seed was 26.2 mg/g. The aim of this article is to study influence of addition of milk thistle pressed parts in feed ration on liver histology and weight increase of laboratory rats. The hypothesis is that the feeding addition - milk thistle seed pressed parts has positive effect on weight performance and liver histology. Does the feeding addition have any effect on these health indicators? Does feeding of milk thistle seed pressed parts have any sense? In results, the groups with addition of milk thistle had significant bigger average gain increases than the control group. Histological results vary considerably among groups of rats. All rats in the control group had dystrophic liver with sinusoidal congestion. In most rats of the group A, the dystrophy was minimal without congestion. On the other hand, most of rats of the group B had liver dystrophy caused by large droplets steatosis with congestion. All rats in control group C were found to have significant dystrophy caused by steatosis. The results indicate rats receiving the addition of milk thistle pressed parts in their feed had a lower incidence of liver steatosis due to the hepatoprotective effects of silymarin.en
dc.format33-39
dc.publisherZdruzenie HACCP Consulting
dc.relation.ispartofPotravinárstvo
dc.relation.urihttps://doi.org/10.5219/864
dc.rightsCC BY 3.0
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/
dc.subjectGrowth performanceen
dc.subjectHistologyen
dc.subjectSilybum marianumen
dc.subjectSilymarinen
dc.titleInfluence of milk thistle pressed parts on rats liver histologyen
dc.typeJ_ČLÁNEK
dc.date.updated2021-06-15T00:02:14Z
dc.description.versionOA
local.identifier.doi10.5219/864
local.identifier.scopus2-s2.0-85041514377
local.number1
local.volume12
local.identifier.obd43914708
local.identifier.e-issn1337-0960
dc.project.IDAF - IGA - 2016 - tym004
dc.project.IDNové poznatky v pěstování a využití ostropestřce mariánského (Silybum Marianum L.) v zemědělství
dc.identifier.orcidDočkalová, Hana 0000-0002-6585-5443
dc.identifier.orcidHorký, Pavel 0000-0001-6074-785X
dc.identifier.orcidZeman, Ladislav 0000-0001-5283-5235
dc.identifier.orcidSkládanka, Jiří 0000-0002-7179-7606
local.contributor.affiliationAF


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CC BY 3.0
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