Browsing by Author "Merlos Rodrigo, Miguel Ángel"

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    • Antibacterial activity of the novel peptide Pac-525 with the RGD motif against intracellular Escherichia coli 

      Coufalová, Martina; Merlos Rodrigo, Miguel Ángel; Michálková, Hana; Milosavljević, Vedran; Hrazdilová, Kristýna; Žůrek, Luděk; Číhalová, Kristýna (Nature Publishing Group, 2025)
      Infections caused by invasive intracellular bacteria pose major therapeutic challenges due to pathogen survival and growth inside of host cells as well as the low intracellular accessibility for conventional antibiotics. ...

    • Metallothionein-3 is a multifunctional driver that modulates the development of sorafenib-resistant phenotype in hepatocellular carcinoma cells 

      Merlos Rodrigo, Miguel Ángel; Michálková, Hana; Jiménez Jiménez, Ana María; Petrlák, František; Do, Tomáš; Sivák, Ladislav; Haddad, Yazan Abdulmajeed Eyadh; Kubíčková, Petra; de los Rios, Vivian; Casal, J. Ignacio; Serrano-Macia, Marina; Delgado, Teresa C.; Boix, Loreto; Bruix, Jordi; Chantar, Maria L. Martinez; Adam, Vojtěch; Heger, Zbyněk (BioMed Central Ltd., 2024)
      Background & aims Metallothionein-3 (hMT3) is a structurally unique member of the metallothioneins family of low-mass cysteine-rich proteins. hMT3 has poorly characterized functions, and its importance for hepatocellular ...