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Prohlížení dle autora "Adam, Vojtěch"

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    • Náhled

      Amalgam Electrode-Based Electrochemical Detector for On-Site Direct Determination of Cadmium(II) and Lead(II) from Soils 

      Nejdl, Lukáš; Kynický, Jindřich; Brtnický, Martin; Vaculovičová, Markéta; Adam, Vojtěch (MDPI AG (Multidisciplinary Digital Publishing Institute-MDPI), 2017)
      Toxic metal contamination of the environment is a global issue. In this paper, we present a low-cost and rapid production of amalgam electrodes used for determination of Cd(II) and Pb(II) in environmental samples (soils ...
    • Náhled

      Anticarcinogenic effect of spices due to phenolic and flavonoid compounds-in vitro evaluation on prostate cells 

      Lacková, Zuzana; Buchtelová, Hana; Buchtová, Žaneta; Klejdus, Bořivoj; Heger, Zbyněk; Brtnický, Martin; Kynický, Jindřich; Zítka, Ondřej; Adam, Vojtěch (MDPI AG (Multidisciplinary Digital Publishing Institute-MDPI), 2017)
      This study shows the effects of spices, and their phenolic and flavonoid compounds, on prostate cell lines (PNT1A, 22RV1 and PC3). The results of an MTT assay on extracts from eight spices revealed the strongest inhibitory ...
    • Náhled

      Graphene Oxide as a Nanocarrier for Biochemical Molecules: Current Understanding and Trends 

      Mukherjee, Soumajit; Bytešníková, Zuzana; Ashrafi, Amirmansoor; Adam, Vojtěch; Richtera, Lukáš (MDPI AG (Multidisciplinary Digital Publishing Institute-MDPI), 2020)
      The development of an advanced and efficient drug delivery system with significant improvement in its efficacy and enhanced therapeutic value is one of the critical challenges in modern medicinal biology. The integration ...
    • Náhled

      Homology modeling in the time of collective and artificial intelligence 

      Yakoub Hassan Hameduh, Tareq; Haddad, Yazan Abdulmajeed Eyadh; Adam, Vojtěch; Heger, Zbyněk (Elsevier Science BV, 2020)
      Homology modeling is a method for building protein 3D structures using protein primary sequence and utilizing prior knowledge gained from structural similarities with other proteins. The homology modeling process is done ...
    • Náhled

      Magnetocaloric-Responsive Hydrogel Nanoarchitectonics for Pyroptosis-Relay-Immunotherapy to Suppress Post-Operation Tumor Recurrence and Metastasis 

      Wang, Siyu; Jing, Huaqing; Yang, Rui; Heger, Zbyněk; Křížková, Soňa; Zhou, Yue; Liang, Xiaoyang; Adam, Vojtěch; Li, Nan (Wiley-VCH Verlag GmbH, 2024)
      Although a widely used option in contemporary anticancer treatment, surgery still causes serious issues, including post-operation recurrence and the development of metastases. Immunotherapy, often following surgical resection ...
    • Náhled

      Metallothionein-3 is a multifunctional driver that modulates the development of sorafenib-resistant phenotype in hepatocellular carcinoma cells 

      Merlos Rodrigo, Miguel Ángel; Michálková, Hana; Jiménez Jiménez, Ana María; Petrlák, František; Do, Tomáš; Sivák, Ladislav; Haddad, Yazan Abdulmajeed Eyadh; Kubíčková, Petra; de los Rios, Vivian; Casal, J. Ignacio; Serrano-Macia, Marina; Delgado, Teresa C.; Boix, Loreto; Bruix, Jordi; Chantar, Maria L. Martinez; Adam, Vojtěch; Heger, Zbyněk (BioMed Central Ltd., 2024)
      Background & aims Metallothionein-3 (hMT3) is a structurally unique member of the metallothioneins family of low-mass cysteine-rich proteins. hMT3 has poorly characterized functions, and its importance for hepatocellular ...
    • Náhled

      Preparation and Optimisation of Cross-Linked Enzyme Aggregates Using Native Isolate White Rot Fungi Trametes versicolor and Fomes fomentarius for the Decolourisation of Synthetic Dyes 

      Vršanská, Martina; Voběrková, Stanislava; Jimenez Jimenez, Ana Maria; Strmiska, Vladislav; Adam, Vojtěch (MDPI AG (Multidisciplinary Digital Publishing Institute-MDPI), 2018)
      The key to obtaining an optimum performance of an enzyme is often a question of devising a suitable enzyme and optimisation of conditions for its immobilization. In this study, laccases from the native isolates of white ...
    • Náhled

      Reduced graphene oxide-based nanometal-composite containing copper and silver nanoparticles protect tomato and pepper against Xanthomonas euvesicatoria infection 

      Bytešníková, Zuzana; Pečenka, Jakub; Tekielska, Dorota Anna; Kiss, Tomáš; Švec, Pavel; Ridošková, Andrea; Bezdička, Petr; Pekárková, Jana; Eichmeier, Aleš; Pokluda, Robert; Adam, Vojtěch; Richtera, Lukáš (Springer International Publishing AG, 2022)
      Xanthomonas euvesicatoria (Xe) is of the genera Xanthomonas, which causes a bacterial spot disease that affects tomato and pepper plants, resulting in significant economic losses. Commonly used bactericides lead to pathogen ...
    • Náhled

      Rotamer Dynamics: Analysis of Rotamers in Molecular Dynamics Simulations of Proteins 

      Haddad, Yazan Abdulmajeed Eyadh; Adam, Vojtěch; Heger, Zbyněk (Biophysical Society, 2019)
      Given by χ torsional angles, rotamers describe the side-chain conformations of amino acid residues in a protein based on the rotational isomers (hence the word rotamer). Constructed rotamer libraries, based on either protein ...
    • Náhled

      Smart bactericide based on reduced graphene oxide decorated with copper and zinc nanoparticles 

      Bytešníková, Zuzana; Pečenka, Jakub; Tekielska, Dorota Anna; Pekárková, Jana; Ridošková, Andrea; Bezdička, Petr; Kiss, Tomáš; Eichmeier, Aleš; Adam, Vojtěch; Richtera, Lukáš (Springer International Publishing AG, 2023)
      Graphene oxide (GO) synthesised by modified Tour's method was decorated with copper and zinc nanoparticles (NPs) and simultaneously reduced by sodium borohydride to obtain a nanocomposite of reduced GO with copper and zinc ...
    • Náhled

      Synergistic antibacterial action of the iron complex and ampicillin against Staphylococcus aureus 

      Košarišťanová, Ludmila; Řiháček, Martin; Suchá, Františka; Milosavljević, Vedran; Švec, Pavel; Dorazilova, Jana; Vojtova, Lucy; Antal, Peter; Kopel, Pavel; Patočka, Zdeněk; Adam, Vojtěch; Žůrek, Luděk; Doleželíková, Kristýna (BioMed Central Ltd., 2023)
      Objectives: Resistance to antibiotics among bacteria of clinical importance, including Staphylococcus aureus, is a serious problem worldwide and the search for alternatives is needed. Some metal complexes have antibacterial ...
    • Náhled

      Synthesis and characterization of TiO2 nanoparticles combined with geraniol and their synergistic antibacterial activity 

      Younis, Almotasem Bellah; Milosavljević, Vedran; Fialová, Tatiana; Šmerková, Kristýna; Michálková, Hana; Švec, Pavel; Antal, Peter; Kopel, Pavel; Adam, Vojtěch; Žůrek, Luděk; Doleželíková, Kristýna (BioMed Central Ltd., 2023)
      Background The emergence of antibiotic resistance in pathogenic bacteria has become a global threat, encouraging the adoption of efficient and effective alternatives to conventional antibiotics and promoting their use as ...

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