Browsing by Author "Adam, Vojtěch"
Now showing items 1-8 of 8
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Amalgam Electrode-Based Electrochemical Detector for On-Site Direct Determination of Cadmium(II) and Lead(II) from Soils
Nejdl, Lukáš; Kynický, Jindřich; Brtnický, Martin; Vaculovičová, Markéta; Adam, Vojtěch (MDPI AG (Multidisciplinary Digital Publishing Institute-MDPI), 2017)Toxic metal contamination of the environment is a global issue. In this paper, we present a low-cost and rapid production of amalgam electrodes used for determination of Cd(II) and Pb(II) in environmental samples (soils ... -
Anticarcinogenic effect of spices due to phenolic and flavonoid compounds-in vitro evaluation on prostate cells
Lacková, Zuzana; Buchtelová, Hana; Buchtová, Žaneta; Klejdus, Bořivoj; Heger, Zbyněk; Brtnický, Martin; Kynický, Jindřich; Zítka, Ondřej; Adam, Vojtěch (MDPI AG (Multidisciplinary Digital Publishing Institute-MDPI), 2017)This study shows the effects of spices, and their phenolic and flavonoid compounds, on prostate cell lines (PNT1A, 22RV1 and PC3). The results of an MTT assay on extracts from eight spices revealed the strongest inhibitory ... -
Graphene Oxide as a Nanocarrier for Biochemical Molecules: Current Understanding and Trends
Mukherjee, Soumajit; Bytešníková, Zuzana; Ashrafi, Amirmansoor; Adam, Vojtěch; Richtera, Lukáš (MDPI AG (Multidisciplinary Digital Publishing Institute-MDPI), 2020)The development of an advanced and efficient drug delivery system with significant improvement in its efficacy and enhanced therapeutic value is one of the critical challenges in modern medicinal biology. The integration ... -
Homology modeling in the time of collective and artificial intelligence
Yakoub Hassan Hameduh, Tareq; Haddad, Yazan Abdulmajeed Eyadh; Adam, Vojtěch; Heger, Zbyněk (Elsevier Science BV, 2020)Homology modeling is a method for building protein 3D structures using protein primary sequence and utilizing prior knowledge gained from structural similarities with other proteins. The homology modeling process is done ... -
Magnetocaloric-Responsive Hydrogel Nanoarchitectonics for Pyroptosis-Relay-Immunotherapy to Suppress Post-Operation Tumor Recurrence and Metastasis
Wang, Siyu; Jing, Huaqing; Yang, Rui; Heger, Zbyněk; Křížková, Soňa; Zhou, Yue; Liang, Xiaoyang; Adam, Vojtěch; Li, Nan (Wiley-VCH Verlag GmbH, 2024)Although a widely used option in contemporary anticancer treatment, surgery still causes serious issues, including post-operation recurrence and the development of metastases. Immunotherapy, often following surgical resection ... -
Preparation and Optimisation of Cross-Linked Enzyme Aggregates Using Native Isolate White Rot Fungi Trametes versicolor and Fomes fomentarius for the Decolourisation of Synthetic Dyes
Vršanská, Martina; Voběrková, Stanislava; Jimenez Jimenez, Ana Maria; Strmiska, Vladislav; Adam, Vojtěch (MDPI AG (Multidisciplinary Digital Publishing Institute-MDPI), 2018)The key to obtaining an optimum performance of an enzyme is often a question of devising a suitable enzyme and optimisation of conditions for its immobilization. In this study, laccases from the native isolates of white ... -
Reduced graphene oxide-based nanometal-composite containing copper and silver nanoparticles protect tomato and pepper against Xanthomonas euvesicatoria infection
Bytešníková, Zuzana; Pečenka, Jakub; Tekielska, Dorota Anna; Kiss, Tomáš; Švec, Pavel; Ridošková, Andrea; Bezdička, Petr; Pekárková, Jana; Eichmeier, Aleš; Pokluda, Robert; Adam, Vojtěch; Richtera, Lukáš (Springer International Publishing AG, 2022)Xanthomonas euvesicatoria (Xe) is of the genera Xanthomonas, which causes a bacterial spot disease that affects tomato and pepper plants, resulting in significant economic losses. Commonly used bactericides lead to pathogen ... -
Rotamer Dynamics: Analysis of Rotamers in Molecular Dynamics Simulations of Proteins
Haddad, Yazan Abdulmajeed Eyadh; Adam, Vojtěch; Heger, Zbyněk (Biophysical Society, 2019)Given by χ torsional angles, rotamers describe the side-chain conformations of amino acid residues in a protein based on the rotational isomers (hence the word rotamer). Constructed rotamer libraries, based on either protein ...