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dc.contributor.authorSarris, Jerome
dc.contributor.authorPerkins, Daniel
dc.contributor.authorCribb, Lachlan
dc.contributor.authorSchubert, Violeta
dc.contributor.authorOpaleye, Emerita
dc.contributor.authorBouso, José Carlos
dc.contributor.authorScheidegger, Milan
dc.contributor.authorAicher, Helena
dc.contributor.authorSimonova, Hana
dc.contributor.authorHorák, Miroslav
dc.contributor.authorGalvão-Coelho, Nicole Leite
dc.contributor.authorCastle, David
dc.contributor.authorTófoli, Luís Fernando
dc.date.accessioned2022-09-21T00:02:14Z
dc.date.available2022-09-21T00:02:14Z
dc.date.issued2021
dc.identifier.issn2666-9153 Sherpa/RoMEO, JCR
dc.identifier.urihttps://repozitar.mendelu.cz/xmlui/handle/20.500.12698/1622
dc.description.abstractBackground: Ayahuasca is a psychoactive Amazonian brew which has emerging data indicating that it has antidepressant and anxiolytic properties. Methods: This paper uses data from the Global Ayahuasca Project (GAP), which was undertaken across 2017-2020 and involved 11912 people, to examine the perceived effects of Ayahuasca consumption on affective symptoms. The study focused on the subsample reporting depression or anxiety diagnoses at time of Ayahuasca consumption. Results: Of participants reporting depression (n = 1571) or anxiety (n = 1125) at the time of consuming Ayahuasca, 78% reported that their depression was either 'very much' improved (46%), or 'completely resolved' (32%); while 70% of those with anxiety reported that their symptoms were 'very much' improved (54%), or 'completely resolved' (16%). A range of factors were associated with greater reported affective symptoms improvement, including subjective mystical experience, number of Ayahuasca sessions, and number of personal psychological insights experienced. 2.7% and 4.5% of drinkers with depression or anxiety, respectively, reported worsening of symptoms. Limitations: This study is recognized as a cross-sectional analysis which cannot assess treatment efficacy. Selection bias may exist due to survey-respondents with favorable experience being potentially biased towards participation. Conclusions: Drinkers of Ayahuasca in naturalistic settings perceived remarkable benefits for their affective symptoms in this survey assessment. There is no obvious evidence of negative mental health effects being associated with long-term consumption. Additional randomized controlled trial evidence is required to establish the efficacy of Ayahuasca in affective disorders, and to understand the worsened symptoms reported by a small percentage of drinkers.en
dc.format100098
dc.publisherElsevier Science BV
dc.relation.ispartofJournal of Affective Disorders Reports
dc.relation.urihttps://doi.org/10.1016/j.jadr.2021.100098
dc.rightsCC BY-NC-ND 4.0
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectAyahuascaen
dc.subjectPsychedelicsen
dc.subjectMental healthen
dc.subjectDepressionen
dc.subjectAnxietyen
dc.subjectEthnobotanyen
dc.titleAyahuasca Use and Reported Effects on Depression and Anxiety Symptoms: An International Cross-Sectional Study of 11,912 Consumersen
dc.typeJ_ČLÁNEK
dc.date.updated2022-09-21T00:02:14Z
dc.description.versionOA
local.identifier.doi10.1016/j.jadr.2021.100098
local.identifier.scopus2-s2.0-85105396696
local.numberApril
local.volume4
local.identifier.obd43920739
local.identifier.e-issn2666-9153
dc.identifier.orcidHorák, Miroslav 0000-0001-8327-8785
local.contributor.affiliationFRRMS


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Zobrazit minimální záznam

CC BY-NC-ND 4.0
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