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dc.contributor.authorVenusová, Eva
dc.contributor.authorKolesarova, Adriana
dc.contributor.authorHorký, Pavel
dc.contributor.authorSláma, Petr
dc.date.accessioned2022-08-18T00:02:13Z
dc.date.available2022-08-18T00:02:13Z
dc.date.issued2021
dc.identifier.issn2072-6643 Sherpa/RoMEO, JCR
dc.identifier.urihttps://repozitar.mendelu.cz/xmlui/handle/20.500.12698/1614
dc.description.abstractThe aim of this publication is to compile a summary of the findings regarding punicalagin in various tissues described thus far in the literature, with an emphasis on the effect of this substance on immune reactions. Punicalagin (PUN) is an ellagitannin found in the peel of pomegranate (Punica granatum). It is a polyphenol with proven antioxidant, hepatoprotective, anti-atherosclerotic and chemopreventive activities, antiproliferative activity against tumor cells; it inhibits inflammatory pathways and the action of toxic substances, and is highly tolerated. This work describes the source, metabolism, functions and effects of punicalagin, its derivatives and metabolites. Furthermore, its anti-inflammatory and antioxidant effects are described.en
dc.format2150
dc.publisherMDPI AG (Multidisciplinary Digital Publishing Institute-MDPI)
dc.relation.ispartofNutrients
dc.relation.urihttps://doi.org/10.3390/nu13072150
dc.rightsCC BY 4.0
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectpunicalaginen
dc.subjectellagic aciden
dc.subjectapoptosisen
dc.subjectproliferationen
dc.subjectimmune cellsen
dc.subjectmetabolismen
dc.titlePhysiological and Immune Functions of Punicalaginen
dc.typeJ_ČLÁNEK
dc.date.updated2022-08-18T00:02:12Z
dc.description.versionOA
local.identifier.doi10.3390/nu13072150
local.identifier.scopus2-s2.0-85108257202
local.identifier.wos000676676100001
local.number7
local.volume13
local.identifier.obd43921390
local.identifier.e-issn2072-6643
dc.project.ID8X20023
dc.project.IDDopad trávicích a vstřebávacích procesů na konečnou biologickou aktivitu rostlinných fytonutrientů: skutečná přidaná hodnota pro zdraví
dc.identifier.orcidVenusová, Eva 0000-0003-1782-6338
dc.identifier.orcidHorký, Pavel 0000-0001-6074-785X
dc.identifier.orcidSláma, Petr 0000-0003-0570-259X
local.contributor.affiliationAF


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CC BY 4.0
Except where otherwise noted, this item's license is described as CC BY 4.0